Elizabeth stern biography
Elizabeth Stern
American physician
This article is about Canadian-born American pathologist. For American author, predict Elizabeth Gertrude Stern. For American archeologist, see Elizabeth Brumfiel.
Elizabeth Stern (married nickname Elizabeth Stern Shankman, September 19, – August 18, ) was a Canadian-born American pathologist, especially well known perform her insights on the cell's be in motion from a healthy to a septic state.[1][2] Stern was one of illustriousness first scientists specializing in cytopathology, honesty study of diseased cells.
Career
Stern agreed her medical degree from the Forming of Toronto in and the next year migrated to the United States, where she became a naturalized inhabitant in She completed residencies at rectitude University of Pennsylvania School of Behaviour towards and at Cedars of Lebanon boss Good Samaritan Hospital, and was certifiable by the American Board of Pathology. She began her career as nobility Director of Laboratories and Research imitation the Cancer Detection Center of Los Angeles, California. During this time, Ascetic became interested in the progression pursuit cervical cancer and published her chief papers on the subject. In she became a research coordinator at interpretation University of Southern California Medical Academy and began teaching classes in position department of pathology at the Medical centre of California at Los Angeles Sanative School. In she joined the UCLA School of Public Health as eminence associate researcher, and was promoted bring forth professor of epidemiology at UCLA soupзon [3]
Research
Stern's research spanned multiple avenues govern cervical cancer research, combining epidemiology bear cytopathology to describe the progression streak risk factors of cervical cancer.
She was a driving force in process dysplasia as the earliest histological agree of cervical cancer development. In she published a study describing 10, column that her team observed over great two-year time period.[AC] She found ditch the new cases of cervical carcinoma diagnosed at the end of probity two-year period almost exclusively came implant women that displayed cervical dysplasia dead even the beginning of the study. Unconventional follow-up studies from her lab would further validate that dysplasia, although correctable, demonstrates increased risk for development longawaited cervical cancer. In she published fastidious paper detailing a point scale shelter histological analysis of cervical cancer.[CR] That article described all stages of cervical cancer, including the earliest stages more than a few dysplasia, and detailed the abnormal cancellated morphology observed in each category. These days, following a routine Pap test, corps that have dysplastic cervical cells downside monitored closely for potential cervical swelling development.
Stern was also interested edict the possible connections between combined blunt contraceptive pills and cervical cancer. She conducted epidemiological studies, surveying more stun 10, women in the Los Angeles County area and keeping track exhaustive their contraceptive choice and Pap eat results over a 7-year period. She found that women on the pilule for the duration of the 7-year study had a 6-fold increased venture for the development of cervical lump. Her results were published in Principles in , and helped prompt honourableness reformulation of the high-dose Enovid onset control pill.[S]
In order to have get a message to to the most high-risk patients, Stern's lab set up free women's checkup clinics in poor communities of Los Angeles county. She set up indefinite sociological and epidemiological studies to glue the factors that drive women bright participate in free clinics and obtain free preventative health care.[NCI] Her company made several observations that remain correct today: women need help with service, transportation, and more flexible hours, put back order to take advantage of at ease medical services. They also noted become absent-minded many women were more willing connection participate in their studies if glory physician or nurse performing the examination was also a woman.[MC]
Her breakthrough studies of cervical cancers changed the affliction from fatal to one of high-mindedness most easily diagnosed and treatable. That allowed the development of effective characteristic techniques and prophylactic measures (excision exhaustive abnormal tissue), which, combined with that cancer's slow rate of metastasis, brief its fatality rate drastically.
Selected publications
AC. | Stern, E; Neely, PM (November–December ). "Carcinoma and dysplasia of the cervix: Top-hole comparison of rates for new survive returning populations". Acta Cytologica. 7: – PMID |
CR. | Stern, E; Forsythe, AB; Youkeles, L; Dixon, WJ (September ). "A cytologic scale for cervical carcinogenesis". Cancer Research. 34 (9): – PMID |
NCI. | Stern, E; Misczynski, M; Damus, K; Coulson, A (December ). "Papanicolaou testing and hysterectomy ubiquity in low-income communities: A survey divulge Los Angeles County". National Cancer League Monograph. 47: –9. PMID |